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Cat#：139P76
序列（三字母）：Z-Phe-Lys-2,4,6-trimethylbenzoyloxy-methylketone trifluoroacetate salt
序列（單字母）：Z-FK-ck
類似名：Z-FK-ck
分子式：C??H??N?O?
分子量：587.72
CAS#：118253-05-7
合成方法：Synthetic
存儲條件：-20 ± 5 °C
描述：Z-FK-ck is a very effective in vivo cathepsin B inhibitor in rats. It inhibited rat liver cathepsin B activity ex vivo with ED?? = 5 mg/kg intraperitoneally and 18 mg/kg orally at 4-5 h postdose, and 2.4 mg/kg subcutaneously at 24 h postdose. It also inhibited rat cathepsin B activity in heart and skeletal muscle with ED?? = 0.1 and 1.0 mg/kg subcutaneously at 20 h postdose. Z-FK-ck is an inhibitor of gingipain K.