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Cat#：203P18
序列（三字母）：H-Glu-Leu-Asp-[(2R,4S,5S)-5-amino-4-hydroxy-2,7-dimethyl-octanoyl]-Ala-Glu-Phe-OH
序列（單字母）：ELD[(2R,4S,5S)-5-amino-4-hydroxy-2,7-dimethyl-octanoyl]AEF
分子式：C??H??N?O??
分子量：908.02
CAS#：1349991-28-1
合成方法：Synthetic
存儲(chǔ)條件：-20 ± 5 °C
應(yīng)用：Alzheimer´s Disease
描述：Glu-Leu-Asp-Leu-psi[CHOH-CH?]-Ala-Ala-Glu-Phe (ELDL-psi[CHOH-CH?]-AAEF), a potent inhibitor for human brain memapsin-2 (β-secretase) with a Ki-value of 0.3 nM. The hydroxyethylene isostere of the Leu-Ala motif functions as a mimic of the transition state.